Optimizations for busy DB??

We are running a Database that is having between 100-500 simultaneous
accesses at any given time.  Are their any flags, switches or
optimizations on the postgres level that can be done?  such as options
passed to postgres etc?  We run 6.3.2, and start it like:

su postgres -c '/usr/bin/postmaster -i -S -D/var/lib/pgsql

Thanks for any help.

Brian


-----------------------------------------------------
Brian Feeny (BF304)     signal@shreve.net   
318-222-2638 x 109	http://www.shreve.net/~signal      
Network Administrator   ShreveNet Inc. (ASN 11881)